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刘忠—主任技师

发布时间:2022-06-21 【字号: 浏览次数:
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       刘忠,博士,毕业于德国洪堡大学,协和学者特聘教授,博士生导师。入选四川省学术和技术带头人,全国抗击新冠肺炎疫情先进个人等称号。主要从事临床输血的安全和有效性研究,在感染性输血安全、精准输血及血液保存方面有较深入的研究。先后发表论文200多篇,其中SCI收录文章近百篇,期刊包括JAMA、ACSNano、Haematol等,单篇他引最高700余次,主编专著5本,专利10余项,成果转化3项。
 
研究方向
     临床输血、血液安全、血液保存等
 
社会任职及荣誉
       7022至尊国际至尊享受输血医学系执行主任、中国医学科学院输血不良反应研究重点实验室主任、7022至尊国际至尊享受副所长、中华预防医学会血液安全专业委员会主任委员、四川省输血协会理事长、《中国输血杂志》主编。第41届国际低温医学、生物学大会(CRYO2004)秘书长,第49届国际低温生物学大会(CRYO2017)副主席等。获省部级科技进步奖5项
 
承担科研项目
  1. 中国医学科学院新冠科技攻关项目恢复期血浆治疗新冠肺炎临床应用研究2020
  2. 国际血液管理模式的研究,国家卫生健康委医政医管局委托项目2018-2019
  3. 中国医学科学院输血不良反应重点实验室,中国医学科学院2017-2020
  4. 医学健康与创新工程,《输血不良反应发生机制与干预》, 2016-2020
  5. 科技部科研院所技术开发项目,《我国输血传播病原体核酸检测关键技术研究》,2014-2017
  6. 国家自然科学基金面上项目,《冻干红细胞残余水的性质及其应用研究》,2013-2017
  7. 国家卫生和计划生育委员会医政医管局委托项目《血液筛查策略与血液安全》,2016
  8. 国家卫生和计划生育委员会法制司委托项目《全血和成份血使用》卫生标准制定2015-2016
  9. 国家卫生和计划生育委员会法制司委托项目《全血和成份血制备》卫生标准制定2019-2022
  10. 国家卫生计生委医政医管局委托项目,《献血法》修订草案研究,2015-2016
  11. 国家卫生计生委医政医管局委托项目《初筛反应阳性献血者确证与召回策略研究》,2013-2016
  12. 国家卫生计生委医政医管局委托项目《输血传播疾病保险分担机制的研究》,2013-2015
  13. 国家卫生计生委医政医管局委托项目,《献血法》修订背景研究,2014-2016
  14. 7022至尊国际至尊享受《输血医学双导师制教育改革项目》,2014-2016
  15. 7022至尊国际至尊享受,《输血医学研究生培养模式的研究》,2012-2015
  16. 四川省脐带血干细胞库,脐带血安全有效性系列技术研究与应用,2014-2017
  17. RhD免疫球蛋白的开发研究,新疆德源合作项目,2013-2016
  18. 国家卫生计生委医政医管局委托项目,血站富余血浆用于血液制品生产可行性研究,2013-2016
  19. 输血医学研究生培养模式研究,2012-2016
代表论著
       著作
  1. 中国输血不良反应报告(2018–2020年),人民卫生出版社. 2021.08(主编)
  2. 全血和成分血使用标准释义,人民卫生出版社. 2019.09(主编)
  3. 血液管理的法制化历程,人民卫生出版社. 2019.02(主编)
  4. 《中华输血学》(第二版),人民卫生出版社. 2022 (副主编)
  5. 《中华输血学》(第一版),人民卫生出版社. 2022 (副主编)
  6. Prenatal Diagnosis. Methods in molecular biology. Humana Press 2008-May-09;444: DOI: 10.1007/978-1-59745-066-9_16
  7. High-throughput Testing for the Determination of the Fetal Rh Factor in Maternal Plasma. 2008-NOV-21
 
        代表性论文
  1. Kong Y, Tian X, He R, Zhong Liu*. The accumulation of exosome-associated microRNA-1246 and microRNA-150-3p in human red blood cell suspensions. J Transl Med. 2021;19(1).
  2. Yin Y, Li L, Gong L, Xu H, Liu Z*. Effects of riboflavin and ultraviolet light treatment on pathogen reduction and platelets [published online ahead of print, 2020 Aug 31. Transfusion. 2020;10.
  3. He R, Kong Y, Fang P, Li L, Shi H, Liu Z*. Integration of quantitative proteomics and metabolomics reveals tissue hypoxia mechanisms in an ischemic-hypoxic rat model. J Proteomics. 2020;228.
  4. Li L, Tong X, Chen H, Liu Z*, et al. Characteristics and serological patterns of COVID-19 convalescent plasma donors: optimal donors and timing of donation. Transfusion. 2020;10.
  5. XiaomingZhou, Zhong Liu*, et al. Microfiltration-based sequential perfusion: A new approach for improved loading/ unloading of cryoprotectants. Sensors and Actuators: B. Chemical. 2020.
  6. Chen S, Xiao J, Song N, Xu H, Tian L, Liu Z*. A genetic polymorphism of IL17F rs763780 associated with anti-E production in the Han Chinese population. Transfus Apher Sci. 2020;102745.
  7. Li L, Zhang W, Hu Y, Tong X, … Wu Y, Liu Z*. Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial. JAMA. 2020;e2010044.
  8. Li L, Yang R, Wang J, Lv Q, … Wu Y, Liu Z*. Feasibility of a Pilot Program for COVID-19 Convalescent Plasma Collection in Wuhan, China. Transfusion. 2020.
  9. Kong Y, Cai C, Ling L, Zeng L, Wu M, Wu Y, Zhang W, Liu Z*. Successful treatment of a centenarian with coronavirus disease 2019 (COVID-19) using convalescent plasma. Transfus Apher Sci. 2020.
  10. Qiao J, He R, Yin Y, Tian L, Li L, Lian Z, Fang P, Liu Z*. rIL-35 prevents murine transfusion-related acute lung injury by inhibiting the activation of endothelial cells. Transfusion. 2020.
  11. Ma C, Wang S, Wang G, Wu Y, …, Yang L, Feng Y, Yu Y, Liu Z*, Wang D. Protein spectrum changes in exosomes after therapeutic plasma exchange in patients with neuromyelitis optica. J Clin Apher. 2020 Jun;35(3).
  12. Li L, Stansbury LG, Hess JR, Liu Z*. The first transfusions in China. Transfusion. 2020;60(5).
  13. Yu X, Wang Z, Shen Y, Liu Z, … etal. Population-based projections of blood supply and demand, China, 2017-2036. Bull World Health Organ. 2020 Jan 1;98(1).
  14. Li L, Ou S, Huang C, Zhou X, Ge H, …, Wu Y, Liu Z*. The prevalence of human T-cell leukemia virus in blood donors in China. Transfusion. 2019 Jul;59(7).
  15. Peng T, Zhao G, Wang L, Wu J, Cui H, Liang Y, Zhou R, Liu Z*, Wang Q. No impact of perioperative blood transfusion on prognosis after curative resection for hepatocellular carcinoma: a propensity score matching analysis. Clin Transl Oncol. 2018 Jun;20(6).
  16. Ou G, Xu H, Yu H, Liu X, Yang L, Ji X, Wang J, Liu Z*. The roles of HLA-DQB1 gene polymorphisms in hepatitis B virus infection. J Transl Med. 2018 Dec 18;16(1).
  17. Ou G, Liu X, Yang L, Yu H, Ji X, Liu F, Xu H, Qian L, Wang J, Liu Z*. Relationship between HLA-DPA1 mRNA expression and susceptibility to hepatitis B. J Viral Hepat. 2019.
  18. Rui He, Ling Li Yujie Kong, Li Tian, Xue Tian Peng Fang, Maohong Bian, Zhong Liu*. Preventing murine Transfusion-related acute lung injury by expansion of CD4+CD25+FoxP3+ Tregs using IL-2/anti-IL-2 complexes. Transfusion. 2019.
  19. Zhu L, Tong H, Wang S, Yu Y, Liu Z, Li C, Wang D. Effectiveness of a flow-based device using riboflavin photochemistry in damaging blood-borne viral nucleic acids. J Photochem Photobiol B. 2018 Jun.
  20. .Ling Li†,Tingting Han †,…Yanhua Li,Zhong Liu*. The current incidence, prevalence, and residual risk of hepatitis B viral infections among voluntary blood donors in China. Bmc Infectious Diseases, 2017, 17(1).
  21. .Kong Y, Tian X, Liu Z, Tian L. Identification of a novel missense mutation in A allele in a Chinese individual. Transfusion. 2017 Dec;57(12).
  22. Ling L, Ka Yi Li, Ke Yan, …Xiaohua Liang, Zhong Liu*, Yanyun Wu. The History and Challenges of Blood Donor Screening in China. Transfusion Medicine Reviews 2017, 31(2).
  23. Ya Wang, Yanyun Wu, Yongjun Chen, Changqing Li, Li Lu, Jim Aubuchon, Zhong Liu*. Journey towards safer and optimized blood banking practices in China from 1978 to 2015: National strategy and progress. Transfusion 2016, 56(12).
  24. Liu Y, Li C, Wang Y, Zhang Y, Wu B, Ke L, Xu M, Liu G, Liu Z*. Which is safer source plasma for manufacturing in China: apheresis plasma or recovered plasma? Transfusion. 2016 May;56(5).
  25. Li L, Xu T, Yang T, Zang L, … Wu Y, Liu Z*. Establishing a reentry procedure for human immunodeficiency virus screening-reactive donors in China. Transfusion , 2016, 56(1).
  26. Zhou X ,Zhang X,Zhang Y,Hong S,Li L,Liu Z*. Effects of lyophilization and rehydration on membrane surface antigens of human red blood cells. CryoLetters,2016,37(1).
  27. †, †, , §, †, *†, and *†. Quantitative Detection of MicroRNA in One Step via Next Generation Magnetic Relaxation Switch Sensing. ACS Nano, 2016 June 27.
  28. Yu X, Chen W, Liu Z, et al. Safety and current status of blood transfusion in China: an update. Lancet Haematol, 2016, 3(2).
  29. Yong-hua Yin, Chang-qing Li, Zhong Liu*. Blood donation in China: sustaining efforts and challenges in 3 achieving safety and availability. Transfusion,2015,55(10).
  30. Chen Q, Srivastava K, Liu Z, et al. Genotype frequency of human neutrophil antigen-3 polymorphisms in the Yi, Han, and Tibetan populations of China.[J]. Transfusion, 2015, 56(3).
  31. Ye L,Yu H, Li C, Hirsch ML, Zhang L, Samulski RJ,Li W, Liu Z*. Adeno-Associated Virus Vector Mediated Delivery of the HBV Genome Induces Chronic Hepatitis B Virus Infection and Liver Fibrosis in Mice. PLoS One. 2015 Jun15;10(6).
 
联系方式
电话/传真: 028-61648562
E-mail: liuz@ibt.pumc.edu.cn

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